Nuraly Assiya Mambetkyzy
Scientific production and Technical Center, Kazakhstan
Title: The use of carbonized rice husk in the manufacture of carbon monolith for hemosorption
Biography
Biography: Nuraly Assiya Mambetkyzy
Abstract
Extracorporal detoxification-hemosorption is currently a newly developed and studied method. Hemosorption is the process of removing blood toxic substances and metobolites of various spectra. In connection with environmental problems in recent years, interest in hemosorption has increased significantly as a simple, affordable, non-traumatic method of therapy. To expand the scope of this method, it is necessary to create new hemosorbents. At the present time, data has appeared that substantiate the advisability of refusing the use of antibacterial agents in the treatment of acute intestinal infections and the need to strengthen pathogenetic therapy with the aim of minimizing adverse effects on the patient's body. At present, in connection with the expansion of the application area and the creation of new chemicals, as well as the increase in the volume and range of medicines, the importance of studying the study of toxicology - the science of acute and chronic poisoning is growing. The problem of detoxification of the body has a special significance in the treatment of toxicological diseases. Development of materials for hemosorption from available raw materials is an urgent task. In this work, a method has been developed for the use of a carbonized rice husk for the manufacture of a carbon monolith used for hemosorption. The uniqueness of the development lies in the fact that it allows the removal of medium and large molecular weight protein toxins from the patient's blood that are formed during the development of multiple organ failure and which are involved in the manifestation of septic shock. The same hemodialysis works at the membrane level and is able to purify the blood only from low molecular weight toxins. Unlike hemodialysis, hemosorption makes it possible to absorb medium and large molecular toxins. This mechanism is achieved due to the microcellular structure. As a result of the study, it was found that the production of carbon monolith is most optimal with the use of "mother milk", which is obtained by mixing components not of the carbon part. Then to the carbon composition - CRSH the addition of "mother milk". Thus, the developed composition of carbon monolith preparation allows to obtain a plastic mass for the preparation of hemosorbent with a microstructure. The carbon monolith is characterized by a large number of mesopores compared to similar sorbents "dust" which does not swell in an isotonic solution. It has an increased hardness, purity, high hemocompatibility, which reduces the standard anticoagulation allowance by a factor of 1.5.