5th International Congress on Healthcare & Hospital Management
Scientific production and Technical Center, Kazakhstan
Title: Receiving and properties enterosorbent-Safe for the organism drug sorption material
Biography: Alibek Mutushev
According to statistics of the World Health Organization, burns occupy the third place among other injuries, especially in case of natural disasters and military conflicts their number increases dramatically. It is known that among the burned patients with superficial and limited deep burns prevail, accounting for 75-80%. In connection with these, the development and implementation of new innovative wound healing dressings with high efficiency is an urgent problem. Today in the world of surgical practice high absorption capacity dressing is widely used for wound healing. Unfortunately, in Kazakhstan a simple dressing is used without any auxiliary substances for fast wound healing. In this regard, it is urgent to search for and develop new highly effective wound healing materials. The purpose of this research work is to study the healing properties of wound healing dressings. In accordance with the goal, tasks formulated were: modeling of mechanical and burn wounds; application of a wound dressing with activated charcoal from rice husk for the treatment of mechanical and burn wounds. As an object of study, eight monthly white laboratory rats with an average body weight of 220-250 g were used. Studies were performed on 18 laboratory rats. To apply burns to the flame, cotton wool, gauze wipes moistened with alcohol were used and mechanical wounds were applied by damaging the skin with a scalpel.
Dressings in the experimental groups changed every three days, observed epithelialization of wounds and there was a presence or absence of purulent exudate in the wounds. Studies carried out on rats have shown that the wound dressing has a pronounced, wound-healing effect. At the same time, the healing time for wounds came much earlier than in the control. Wound dressing series are more effective in the treatment of mechanical wounds. In all animals with mechanical wounds, partial epithelialization of the wound was observed three days after the application of the wound and eight days after the application of mechanical damage complete wound healing was observed. And in the control group, the complete healing of the mechanical wound was observed only 15 days after the injury was applied. Also, in the treatment of a burn wound, this dressing promoted the rapid healing of wounds in comparison with the control that is within 20 days of the complete healing of the burn wound was observed. The results obtained showed that the wound dressing can be used in the treatment of burn injuries. Carbonized rice husks and colloidal silver that are part of the dressings contribute to the rapid healing of wounds by absorbing the wound by the carbonized rice husk and preventing the formation of purulent exudate with colloidal silver as a potent antiseptic. Based on the experimental results obtained it can be concluded that the dressing can be used in practice for the treatment of burn disease.